v1.16.1

PA - C7 - CHI581 : Chemistry and Biology: Retrosynthesis, Synthesis and Therapeutic Chemi

Domaine > Chimie.

Descriptif

The first part of the course deals with the biomolecule (DNA, proteins) structure and the quantitative assessment of biomolecule/ligand interactions (parameters, measurements, biophysical techniques). A second part presents the development of biologically/therapeutically active metallic complexes. Several roles or activities of the metal center are presented: purely structural role (e.g., enzyme inhibition or protein-protein interactions), ligand exchange effects (DNA-platinum complexes, release of small molecules like CO, and so on), redox activity (ferrocifene, Pt(IV) complexes, catalytically active complexes), and so on.


Language course: English

Credits ECTS: 4

Format des notes

Numérique sur 20

Littérale/grade réduit

Pour les étudiants du diplôme Diplôme d'ingénieur de l'Ecole polytechnique

Pour les étudiants du diplôme M1 Biologie-Santé - Voie Boris Ephrussi-X

Pour les étudiants du diplôme M1 Chimie - Voie Fréderic Joliot-Curie - Ecole Polytechnique

Veuillez patienter