PA - C3B - CHI561 : Total Synthesis and Biosynthesis

Domaine > Chimie.


Definition of a synthon and retrosynthetic analysis ; carbon-carbon bond formation and functional group inter-conversions ; problems of chemo-, regio-, diastereo-, and enantio-selectivity ; impact of new reactions on the strategies and tactics of organic synthesis ; some examples of total syntheses.

Biosynthesis. Main classes of natural products: primary and secondary metabolites ; prebiotic synthesis ; some basic enzymatic reactions ; biosynthesis of polyacetates and polyketides: fatty acids and phenols ; metabolites of shikimic acid ; polyisoprenoids : terpenes and steroids ; biosynthesis of alkaloids.

Requirement: CHI552-Advanced Organic Chemistry and CHI553-Organometallic Chemistry

Language course: English

Credits ECTS: 4

Format des notes

Numérique sur 20

Littérale/grade réduit

Pour les étudiants du diplôme Diplôme d'ingénieur de l'Ecole polytechnique

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