Definition of a synthon and retrosynthetic analysis ; carbon-carbon bond formation and functional group inter-conversions ; problems of chemo-, regio-, diastereo-, and enantio-selectivity ; impact of new reactions on the strategies and tactics of organic synthesis ; some examples of total syntheses.
Biosynthesis. Main classes of natural products: primary and secondary metabolites ; prebiotic synthesis ; some basic enzymatic reactions ; biosynthesis of polyacetates and polyketides: fatty acids and phenols ; metabolites of shikimic acid ; polyisoprenoids : terpenes and steroids ; biosynthesis of alkaloids.
Requirement: CHI552-Advanced Organic Chemistry and CHI553-Organometallic Chemistry
Language course: English
Credits ECTS: 4